Patients and Families

Discover the FDA-approved OCS multi-organ platform technology

Every organ wasted is a life not saved

The majority of donated organs are not utilized for transplantation due to the limitations of cold storage preservation (putting organs on ice in a cooler).

A large and growing clinical demand

OCS Heart has shown a significant reduction of injurious ischemic time compared to cold storage

Lung Failure

>12 Million Americans are diagnosed with COPD
SourceL NIH, 2010

Heart Failure

~650,000 Americans are diagnosed with CHF
Source: Mancini et al. JACC, 2015

OCS Lung has shown an approximate 50% reduction of primary graft dysfunction (PGD) grade 3*

Liver Failure

~ 2.8 Million patients diagnosed with Liver Cirrhosis
Source: Global Burden of Disease Study. Lancet

Cold storage limitations

Cold ischemia

Donated organs placed on ice remain viable only for a limited amount of time. Being maintained in this ischemic state, with no blood supply, for an extended period of time can result in permanent organ damage.

No organ assessment

Because organs placed in cold storage are neither functional nor metabolically active, they cannot be assessed for viability.

Lack of organ optimization

Therapeutic intervention cannot be used to optimize the condition of donor organs, which may negatively impact transplant outcomes.

With Cold Storage

Only 2-3 out of 10 donated thoracic organs are able to be used for transplant

Severe time-dependent injury (ischemia)

No organ optimization capabilities

No assessment of organ viability

30-35% post-transplant complications*

1 U.S. Organ Procurement and Transplant Network (OPTN) 2016 Annual Report
2 The Lancet Respiratory Medicine Journal; Results of OCS Lung INSPIRE Trial; Singh et al.; ISHLT Primary graft dysfunction Incidence, Risk factors and Outcomes ; Transplantation 2019; Vol 103, No.2 336-343.

With OCS Technology

OCS can help deliver a significant increase in organ utilization

Significant reduction in ischemia

Enables organ optimization outside of the human body

Allows for organ viability assessment

Significant improvement of clinical outcomes

*The Lancet Respiratory Medicine Journal; Results of OCS Lung INSPIRE Trial; Results of OCS Heart EXPAND Trial

A Transformative Technology

To overcome the limits of cold storage, the Organ Care System, or OCS™, is a transformative technology designed to better preserve, assess, and maintain donor organs, potentially reducing the number of unused organs by addressing the key limitations of current preservation methods.

Warm blood perfusion

Donor organs are maintained in a living, functioning state, perfused with warm, oxygenated, and nutrient-enriched blood

Organ assessment

The OCS allows physicians to monitor and assess the viability of organs outside the body

Therapeutic intervention and optimization

By replenishing organs with oxygen and nutrients, the health of an organ can be optimized during transport

The only fully-integrated, compact, portable organ system. Shown to improve clinical outcomes.

The TransMedics Organ Care System (OCS) is a fully portable, multi-organ, normothermic preservation and assessment technology that mirrors human physiology, minimizes ischemia, and provides the ability to optimize the organ during transport.

This revolutionary technology allows physicians and institutions to maximize the potential of donor hearts, lungs, and livers while monitoring each organ throughout the entire process, ensuring transplant teams can preserve organs in an optimal condition.